Selected Publications – Nanomedicine
Mirkin, C. A.; Letsinger, R. L.; Mucic, R. C; Storhoff, J. J. “A DNA-based method for rationally assembling nanoparticles into macroscopic materials,” Nature, 1996, 382, 607-609, doi: 10.1038/382607a0.
Rosi, N. L.; Giljohann, D. A.; Thaxton, C. S.; Lytton-Jean, A.; Han, M. S.; Mirkin, C. A. “Oligonucleotide-Modified Gold Nanoparticles for Intracellular Gene Regulation,” Science, 2006, 312, 1027-1030, doi 10.1126/science.1125559.
Jensen, S. A.; Day, E. S.; Ko, C. H.; Hurley, L. A.; Luciano, J. P.; Kouri, F. M.; Merkel, T. J.; Luthi, A. J.; Patel, P. C.; Cutler, J. I.; Daniel, W. L.; Scott, A. W.; Rotz, M. W.; Meade, T. J.; Giljohann, D. A.; Mirkin, C. A.; Stegh, A. H. “Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma,” Science Trans. Med., 2013, 5, 209ra152, doi: 10.1126/scitranslmed.3006839.
Banga, R. J.; Chernyak, N.; Narayan, S. P.; Nguyen, S. T.; Mirkin, C. A. “Liposomal Spherical Nucleic Acids,” J. Am. Chem. Soc., 2014, 136, 9866-9869, doi: 10.1021/ja504845f.
Radovic-Moreno, A. F.; Chernyak, N.; Mader, C. C.; Nallagatla, S.; Kang, R.; Hao, L.; Walker, D. A.; Halo, T. L.; Merkel, T. J.; Rische, C.; Ananatatmula, S.; Burkhart, M.; Mirkin, C. A.; Gryaznov, S. M. “Immunomodulatory Spherical Nucleic Acids,” Proc. Natl. Aca. Sci. USA, 2015, 112, 3892-3897, doi: 10.1073/pnas.1502850112.
Yamankurt, G.; Berns, E. J.; Xue, A.; Lee, A.; Bagheri, N.; Mrksich, M.; Mirkin, C. A. “Exploration of the Nanomedicine-design Space with High-Throughput Screening and Machine Learning,” Nature Biomedical Engineering, 2019, 3, 318-327, doi: 10.1038/s41551-019-0351-1.
Wang, Shuya; Qin, L.; Yamankurt, G.; Skakuj, K.; Huang, Z.; Chen, P.-C.; Dominquez, D.; Lee, A.; Zhang, B.; Mirkin, C. A. “Rational Vaccinology with Spherical Nucleic Acids,” Proc. Natl. Aca. Sci. USA, 2019, 116, 10473-10481, doi: 10.1073/pnas.1902805116.
Callmann, C. E.; Cole, L. E.; Kusmierz, C. D.; Huang, Z.; Horiuchi, D.; Mirkin, C. A. “Tumor Cell Lysate-Loaded Immunostimulatory Spherical Nucleic Acids as Therapeutics for Triple Negative Breast Cancer,” Proc. Natl. Aca. Sci. USA, 2020, 117, 17543-17550, doi: 10.1073/pnas.2005794117.
Samanta, D.; Ebrahimi, S. B.; Kusmierz, C. D.; Cheng, H. F.; Mirkin C. A. “Protein Spherical Nucleic Acids for Live-Cell Chemical Analysis,” J. Am. Chem. Soc., 2020, 142, 13350-13355, doi: 10.1021/jacs.0c06866.
e2119093119. doi: 10.1073/pnas.2119093119
Mirkin C.A. “Spherical nucleic acids as infectious disease vaccine platform” Proc. Natl. Aca. Sci. USA, 2022, 199,Mirkin C.A. “Tuning DNA dissociation from spherical nucleic acids for enhanced immunostimulation’ ACS Nano, 2023 , 17, 17996- 18007,
Paranandi K.S.; Lee A. Stanik, N, Mirkin, C.A. ” Cellular export fate of liposomal spherical nucleic acids” ACS Nano, 2023 , 17, 19000-19010, doi/10.1021/acsnano.3c04608
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